| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8541635 | Journal of Pharmacy Research | 2013 | 6 Pages |
Abstract
The total synthesis of enantiomer of pyrenophorol, non-natural isomer of pyrenophorol, has been accomplished in 12 steps from enantiomerically pure (R)-Propylene oxide prepared by hydrolytic kinetic resolution. Other key steps are Sharpless epoxidation, reductive elimination of iodoepoxide, and Mitsunobu reaction for the construction of the macrolactone.
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Authors
Saroja Nuguri, Naresh Kumar Vuppula, Laxminarayana Eppakayala, Prasad Kottapalli Rajasekhara,