Preparation and characterization of repaglinide loaded ethylcellulose nanoparticles by solvent diffusion technique using high pressure homogenizer

Saturated ethylcellulose ethyl acetate solution facilitates efficient encapsulation of repaglinide at 0.5% PVA. The drug release mechanism is combination of diffusion and erosion. This formulation can increase patient compliance by reduce the number of dosage and incidence of side effects.