Efficient synthesis of novel 3,4,5-triarylisoxazole derivatives and its antifungal activity studies

Novel 3,4,5-triarylisoxazole derivatives were synthesised by Suzuki reaction of 4-bromo-3, 5-diaryl isoxazoles with various boronic acid under microwave condition. The structures of the newly synthesised compounds are characterised by 1H NMR, 13C NMR, LC-MS and screened for their antifungal activity against Aspergillus flavus (NCIM No. 524), Fusarium oxysporum (NCIM No. 1072) and Candida albicans (NCIM No. 3102).