Phosphorylated SIRT1 as a biomarker of relapse and response to treatment with glatiramer acetate in multiple sclerosis

Article ID	Journal	Published Year	Pages	File Type
8624055	Experimental and Molecular Pathology	2018	31 Pages	PDF

Keywords

nuclear factor kappa light chain enhancer of activated B cells Forkhead box protein O H3K9me3 Histone H3 lysine 9 trimethylation CPT ROC RGC-32 RRMs NF-kB HDAC PBMCs EDSS EAE Sirt1 AUC experimental autoimmune encephalomyelitis Biomarker CNS peripheral blood mononuclear cells central nervous system FoxO Expanded Disability Status Scale area under the curve relapsing-remitting multiple sclerosis Multiple sclerosis NAD nicotinamide adenine dinucleotide histone deacetylase glatiramer acetate receiver operating characteristic

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Life Sciences Biochemistry, Genetics and Molecular Biology Clinical Biochemistry

Phosphorylated SIRT1 as a biomarker of relapse and response to treatment with glatiramer acetate in multiple sclerosis

Authors

Jonathan Ciriello, Alexandru Tatomir, Daniel Hewes, Dallas Boodhoo, Freidrich Anselmo, Violeta Rus, Horea Rus,