| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8624114 | Experimental and Molecular Pathology | 2018 | 5 Pages |
Abstract
The present case highlights the potential clinical implications of a R882H-DNMT3A mutated clone that persisted after conventional AML treatment, including alloHSCT. It also reinforces the notion of the importance of cell non-intrinsic factors, such as the hematopoietic-stress induced by chemotherapy and radiotherapy, as drivers of clonal expansion.
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Authors
Iván MartÃn, Blanca Navarro, Eva Villamón, Carlos Solano, Alicia Serrano, Marisa Calabuig, Paula Amat, Fernando Domingo, Rosario Abellán, Francisca GarcÃa, MarÃa Dolores Olivares, Francisco Javier Chaves, Mar Tormo, Juan Carlos Hernández-Boluda,