Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8659029 | Diabetes & Metabolic Syndrome: Clinical Research & Reviews | 2017 | 7 Pages |
Abstract
Lipid modification holds the key to effective secondary prevention of cardiovascular disease (CVD). However there is a controversy on whether it's all about targeting specific lipid sub fractions to a particular level or a direct effect of the agent(s) used or both. This review intends to look into these important issues from an evidence-based perspective. What is the appropriate timing of testing for lipid profile after a cardiovascular event? What is the rationale behind initiating with a high dose statin after an acute coronary event? What is the role of targeting lipid sub fractions beside LDL cholesterol? Is there any role for non-statin based therapy after an acute cardiovascular event? What constitutes a long-term lipid modification strategy in patients post CVD? These are very important questions, which needs to be addressed adequately as well as scientifically. The secondary CVD preventive strategies form a lipid perspective, which requires a thorough review.
Keywords
CHDLDL-Chs-CRPHDL-CDAPTPCIIMPROVE-ITHighly Sensitive C-Reactive ProteinRCTACCNCDSTEMIcTNTVLDL-CMACEPTCANSTEMIFFAAHAACSIL-6PROVE IT-TIMI 22AmIRandomized controlled trialMyocardial infarctionPercutaneous transluminal coronary angioplastyStatinsFree fatty acidinflammationAmerican Heart AssociationST elevation myocardial infarctioninterleukin-6coronary heart diseasecardio vascular diseasecardiovascular diseasechronic kidney diseasecardiac troponin Ttriglyceridemajor adverse cardiac eventsNICEdual antiplatelet therapyCVDAcute coronary syndromeAcute myocardial infarctionbody mass indexBMITumor Necrosis Factor- αTNF-αFibratesLow density lipoprotein-cholesterolHigh density lipoprotein-cholesterolNational Institute for Health and Care Excellencepercutaneous coronary interventionMONICACKDMultinational Monitoring of trends and determinants in Cardiovascular diseasesecondary preventionLipidsAmerican College of CardiologyHDL cholesterolLDL cholesterol
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Authors
Samit Ghosal, Binayak Sinha,