Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8663280 | JACC: Basic to Translational Science | 2018 | 16 Pages |
Abstract
Electrospinning of silk to create nanofibers, which deposit onto a rotating collector. This results in the formation of a pure silk conduit of 1.5 mm internal diameter. These conduits are then implanted into the descending abdominal aorta of Sprague Dawley Rats with end-to-end suturing, and left for 3, 6, 12, and 24 weeks. Endpoint histologic analysis of the explanted grafts demonstrate hyperplasia stabilization, complete endothelialization and excellent blood compatibility.
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Authors
Elysse C. MSc, Miguel MSc, Juichien MSc, Bob S.L. MSc, Nianji MPhil, Alex H.P. BSc, Martin K.C. MD, PhD, Jelena PhD, Steven G. PhD,