Protein Kinase C Inhibition With Ruboxistaurin Increases Contractility and Reduces Heart Size in a Swine Model of HeartÂ Failure With Reduced Ejection Fraction

Article ID	Journal	Published Year	Pages	File Type
8663301	JACC: Basic to Translational Science	2017	15 Pages	PDF

Keywords

ESV RBx ruboxistaurin ADHF HFrEF end-diastolic pressure-volume relationship PRSW EDPVR LVEDV ESPVR DOB EES PLN EDV pKa LVEF PKC Myocardial infarction end-systolic pressure-volume relationship ECG electrocardiogram ischemia–reperfusion left ventricle/ventricular End-diastolic volume Left ventricular end-diastolic volume end-systolic volume Dobutamine Digitalis Acute myocardial infarction DIG acute decompensated heart failure phospholamban LAD heart failure heart failure with reduced ejection fraction Positive inotropy invasive hemodynamics protein kinase A Protein kinase C left anterior descending coronary artery left ventricular ejection fraction

Related Topics

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Protein Kinase C Inhibition With Ruboxistaurin Increases Contractility and Reduces Heart Size in a Swine Model of HeartÂ Failure With Reduced Ejection Fraction

Authors

Thomas E. BA, Hajime PhD, Remus M. BS, Timothy BS, Markus MD, PhD, Giana J. BS, Alexander R. BS, Daohai PhD, Danielle M. PhD, Jon C. MD, Jeffery D. PhD, Steven R. PhD,