Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8675286 | Progress in Cardiovascular Diseases | 2017 | 45 Pages |
Abstract
Mitral regurgitation (MR) is the one of the most frequent valvular heart diseases in the developed world, often requiring surgical correction. Degenerative MR is the most common type of non-ischemic, organic MR in the western world. Since no medical treatment has been shown to be effective in preventing the consequences of volume overload in asymptomatic degenerative MR, risk stratification is essential. Currently, this is achieved using clinical and precisely quantified echocardiographic parameters, with newer technologies like cardiac magnetic resonance gaining increasing prominence. While surgical mitral repair, often performed using minimally invasive/robotic techniques, is the current gold-standard for definitive therapeutic management, there is rapid emergence of percutaneous techniques for mitral valve repair/replacement in cases of degenerative MR. This state-of-the-art-review will discuss the latest knowledge in the natural history, imaging, surgical and percutaneous therapies in patients with degenerative MR.
Keywords
Transcatheter mitral valve implantationPASPRVSPLVEDdLVOTNYHAFMRLVEFLVESDVHDTMVILGEBNPDMRCMRlate gadolinium enhancementCardiac magnetic resonanceNew York Heart AssociationUnited StatesRight ventricularleft ventricle or ventricularvalvular heart diseasetranscatheter mitral valve repairEROAmitral valvedegenerative mitral regurgitationOutcomesright ventricular systolic pressurepulmonary artery systolic pressureleft ventricular global longitudinal strainleft ventricular end diastolic diameterleft ventricular end systolic diameterMETSleft ventricular outflow tractMetabolic equivalentseffective regurgitant orifice areaheart failuremitral regurgitationPulmonary hypertensionbrain natriuretic peptideleft ventricular ejection fraction
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Authors
Milind Y. Desai, Francesco Grigioni, Marco Di Eusanio, Matteo Saccocci, Maurizio Taramasso, Francesco Maisano, Rakesh M. Suri, A. Marc Gillinov,