Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8676210 | Revista Colombiana de Cardiología | 2017 | 12 Pages |
Abstract
Heart failure initially causes myocardial damage that leads to ventricular remodelling. This, in turn, leads to activation of compensatory mechanisms where the kidney plays a fundamental role, as it regulates electrolyte homeostasis and thus the circulating volume. The sympathetic nervous system and the renin angiotensin-aldosterone system lead to the retention of sodium and water, which adversely affects cardiac function. This leads to cardiovascular, renal and myocardial compromise, or a cardiorenal syndrome, which is classified according to its presentation and pathophysiological components. The definition and conceptualization of cardiorenal syndrome includes two-way interactions, where acute and chronic changes of any organ can functionally or structurally affect the ventricular and/or renal function.
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Authors
Javier Eliécer Pereira-RodrÃguez, Lorena Boada-Morales, Damaris RocÃo Niño-Serrato, Myriam Caballero-Chavarro, Gina Rincón-Gonzales, Tania Jaimes-MartÃn, Jésica Melo-Ascanio,