Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8688578 | NeuroImage: Clinical | 2017 | 35 Pages |
Abstract
Early-phase FBB acquisitions correlate on a relative quantitative and visual level with FDG PET scans, irrespective of the amyloid plaque density assessed in late FBB imaging. Thus, early-phase FBB uptake depicts a metabolism-like image, suggesting it as a valid surrogate marker for synaptic dysfunction, which could ultimately circumvent the need for additional FDG PET investigation in diagnosis of dementia.
Keywords
FDGFBB3D-SSPSUVRp.i.FTLD[18F]-fluorodeoxyglucoseFDG PETMNICBFPCCGLMVOImild cognitive impairmentSPECTAlzheimer's diseaseLeftPost Injectionsingle photon emission computed tomographyPositron emission tomographycerebral blood flowvolume of interestright frontotemporal lobar degenerationCognitively Normalposterior cingulate cortexMetabolismCerebellumMontreal Neurological InstituteMCIPETPerfusionCbl
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Authors
Sonja Daerr, Matthias Brendel, Christian Zach, Erik Mille, Dorothee Schilling, Mathias Johannes Zacherl, Katharina Bürger, Adrian Danek, Oliver Pogarell, Andreas Schildan, Marianne Patt, Henryk Barthel, Osama Sabri, Peter Bartenstein, Axel Rominger,