Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8700639 | Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology | 2018 | 5 Pages |
Abstract
Myoepithelioma is a benign salivary gland neoplasm, locally invasive and uncommon in children. The aim of this study is to present and discuss the clinical, morphological and immunohistochemical findings of this tumor in a pediatric patient. This is a case report of a 12-year-old female patient showed a nodular lesion in the palate with osseous resorption with one year of evolution. After incisional biopsy, the histopathological examination revealed encapsulated lesion with proliferation of myoepithelial cells, including plasmacytoid, fusiform and clear cells, arranged in sheets, nests and cords. Immunohistochemical analysis revealed immunostaining for AE1/AE3, p63, cytokeratin-7, calponin, SMA and S-100. Based on these findings, diagnosis of myoepithelioma was confirmed. The lesion was completely removed through enucleation, in follow-up 2 years; there was no recurrence of the tumor. Myoepithelioma of salivary glands although rare in children may be invasive, however it is less aggressive than other tumors, a conservative treatment avoiding facial mutilation in pediatric patients is sufficient in these cases.
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Authors
Luiz Arthur Barbosa da Silva, Leorik Pereira da Silva, Antonio Brunno Gomes Mororó, Adriano Rocha Germano, Márcia Cristina da Costa Miguel,