The challenge in the treatment of central giant cell granuloma - What is the best approach?

The central giant cell granuloma consists of a non-neoplastic benign proliferative process, which represents about 7% of lesions of the jaws. There are many choices to be performed regarding treatment; an aggressive curettage or total resection is traditionally recommended, which ends up being mutilating. Conservative therapies, alternatively or in combination with surgery, are used to minimize the anatomical, functional and esthetic post-surgical damage. Furthermore, there are reported cases of complete regression of the lesions spontaneously. If the treatment results in loss of teeth, the prosthetic rehabilitation phase begins after epithelialization of the surgical wound and focuses on restoring the patients' esthetics, speech and swallowing, as well as their self-esteem. The goal of this study is to discuss therapies and procedures for this pathology, and it also describes two clinical cases: from diagnosis and treatment, to rehabilitation and follow up of these patients. Finally, follow up is crucial for successful treatment.