| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8700784 | Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology | 2017 | 7 Pages |
Abstract
Our findings indicate that selenite induces apoptosis in HOSCC cell lines in a caspase-dependent manner through mitochondrial, death-receptor, and ER stress pathways. In addition, selenite could exhibit antitumor activity by downregulating Akt activation, which plays an important role in cell growth and chemotherapy resistance.
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Authors
Manabu Endo, Hiroshi Hasegawa, Tetsuharu Kaneko, Chihiro Kanno, Tsutomu Monma, Makoto Kano, Fumiaki Shinohara, Tetsu Takahashi,