Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8719105 | Injury | 2017 | 9 Pages |
Abstract
These findings support the view that the positive effects of reaming on fracture healing might result from mechanically grafting the fracture site with a population of skeletal progenitors that contain multipotent cells; transitioning the signalling environment to a less inflammatory state, and enhancing the availability of specific osteogenic and angiogenic factors. A better understanding of the requisite stimuli for optimal bone repair, considering the disturbances made by orthopaedic treatments, will be determinant for the development of innovative treatments for bone repair.
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Authors
Leonardo R. Rocha, Rafaela C. Sartore, Ana C. Leal, Rhayra B. Dias, Maria Eugenia L. Duarte, João Antônio M. Guimarães, Danielle C. Bonfim,