Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8720613 | Annales d'Endocrinologie | 2017 | 10 Pages |
Abstract
Various Kp/NkB agonist/antagonist compounds have been developed during the last ten years, and are currently being evaluated in humans. These molecules have potential applications not only in rare genetic diseases with Kp/NkB alterations, but also in various gonadotrope axis-related diseases or in vitro fertilization. The administration of NkB antagonists in menopausal women represents a real therapeutic advance because of their impressive effect in controlling vasomotor menopausal hot flushes.
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Authors
L. Maione, S. Christin-Maître, P. Chanson, J. Young,