Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8730887 | Revista de Gastroenterología de México | 2017 | 10 Pages |
Abstract
Symptom exacerbation following PPI cessation for at least 7 days correlated with acid reflux severity assessed by Bravo® testing. Patients off PPIs for 7 days had a higher likelihood of experiencing worsening symptoms, compared with those off PPIs for more than 7 days. These findings suggest that when PPIs are held for 7 days or less prior to Bravo® testing, acute worsening of upper GI symptoms due to the abrupt discontinuation of therapy may influence the Bravo® results. The etiology of this may be related to rebound acid hypersecretion and needs to be further elucidated in future studies.
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Authors
R. Schey, S.P. Alla, D. Midani, H.P. Parkman,