Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8736789 | The Brazilian Journal of Infectious Diseases | 2016 | 4 Pages |
Abstract
This work performed a phenotypic and genotypic characterization of 79 clinical isolates of Enterobacteriaceae and Pseudomonadaceae collected in hospitals of Southern Ecuadorin 2013. Our results showed a high incidence of β-lactamases and ESBLs with blaTEM and blaCTX-M as the prevalent genes, respectively. By direct sequencing of PCR amplicons, the different β-lactamases and variants of the genes were also distinguished. Our results revealed a predominance of TEM-1 β-lactamase and the presence of different CTX-M variants with a prevalence of CTX-M-15. Two infrequent CTX-M variants in South America were also identified. To the best of our knowledge, this is one of the first studies describing the genetic characteristics of β-lactamases in Ecuador.
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Authors
Diana Yessenia Calva Delgado, Zorayda Patricia Toledo Barrigas, SofÃa Genoveva Ochoa Astutillo, Ana Paulina Arévalo Jaramillo, Alessio Ausili,