| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8739663 | Journal of Clinical Virology | 2018 | 15 Pages |
Abstract
Serological testing is inappropriate for identifying HEV-viremic blood donors. Acute HEV infection in asymptomatic blood donors can persist for more than 100 days. HEV-RNA clearance coincided with the appearance of anti-HEV IgM/IgG confirming the importance of a B-cell mediated response in clearing acute infections. Anti-HEV IgM and IgG specific for the epitope O2C are associated with the clearance of HEV-viremia.
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Authors
Christian Kraef, Christian Schlein, Jens Hiller, Dirk Westhölter, Ulrike Denzer, Thomas Horvatits, Sven Peine, Ansgar W. Lohse, Marc Lütgehetmann, Susanne Polywka, Sven Pischke,