| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8744558 | Anaerobe | 2018 | 16 Pages |
Abstract
DS-2969b, a novel GyrB inhibitor, transiently and reversibly altered the counts of limited intestinal microbiota at around 10â¯Î¼g/g of faecal levels in rats and monkeys. Considering the high activity of DS-2969b against Clostridium difficile, 10â¯Î¼g/g of faecal levels would be sufficient for clearing C. difficile from the intestine.
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Authors
Manoj Kumar, Tarun Mathur, Vattan Joshi, Dilip J. Upadhyay, Shin-ichi Inoue, Nobuhisa Masuda,