Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8744756 | Clinical Microbiology and Infection | 2018 | 8 Pages |
Abstract
Mechanism-based mathematical approach provides an excellent platform for describing the time course of effect while taking into account the mechanisms of different antibiotics and differing pathogen susceptibilities. This approach allows for the future integration of 'omics' data describing host-pathogen interactions, that will provide a systems-level understanding of the underlying infectious process, and enable the design of effective combination therapies.
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Authors
G.G. Rao, J. Li, S.M. Garonzik, R.L. Nation, A. Forrest,