Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8745004 | Clinical Microbiology and Infection | 2017 | 20 Pages |
Abstract
Isavuconazole displayed broad in vitro activity, similar to that of voriconazole. Up to 15% of C. glabrata, C. tropicalis and A. fumigatus isolates were non-wt, reflecting increased resistance at a reference centre and technical issues. Significant CYP51A alterations were reliably detected applying the isavuconazole breakpoint.
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Authors
K.M.T. Astvad, R.K. Hare, M.C. Arendrup,