| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8749266 | Microbial Pathogenesis | 2018 | 5 Pages |
Abstract
The distribution of LAA among STEC strains isolates from different origins between 2000 and 2015 from cattle, the farm environment, and food and harboring diverse virulence was investigated. The STEC strains were characterized by PCR to detect three modules of LAA and agn43 (as marker of module IV), and phylogenetic groups were determined. LAA was found in 46% of LEE-negative STEC corresponding to serogroups O91, O174, O113, O171, O178, O130 and others. The presence of this PAI is associated with strains harboring stx2 (56%) and belonging to phylogroup B1 (91%). LAA is a novel pathogenicity island associated with strains isolated from Hemolytic Uremic Syndrome cases. Therefore, the results of this study contribute to a better understanding regarding the pathogenicity of this emergent subset of STEC strains harboring LAA as a predictor of virulence of LEE-negative STEC strains.
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Authors
RocÃo Colello, MarÃa Victoria Vélez, Juliana González, David A. Montero, Ana V. Bustamante, Felipe Del Canto, AnalÃa I. EtcheverrÃa, Roberto Vidal, Nora LÃa Padola,