Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8791907 | Experimental Eye Research | 2018 | 6 Pages |
Abstract
We discovered a novel mechanism in pterygium whereby MDM2 suppresses p53 transcriptional activity despite abundant p53 in pterygium. Disruption of MDM2-p53 interaction by Nutlin could be a potential treatment for pterygium.
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Authors
Di Cao, Tsz Kin Ng, Yolanda W.Y. Yip, Alvin L. Young, Chi Pui Pang, Wai Kit Chu, Vishal Jhanji,