| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8918098 | Current Opinion in Systems Biology | 2017 | 9 Pages |
Abstract
Diabetes mellitus is a complex metabolic disease characterized by insulin deficiency and chronically deregulated blood-glucose levels. Treatment strategies based on electronic artificial pancreas systems and human islet transplantations are already available to provide automated and closed-loop glycaemic control, but more sophisticated solutions are urgently needed to provide higher diagnostic accuracy, longer treatment duration, better quality of life and greater safety. In this review, we describe recent breakthroughs in stem cell research and synthetic biology, and critically discuss their future potential from the viewpoints of clinical applicability and marketability.
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Authors
Mingqi Xie, Dominique Aubel, Martin Fussenegger,