Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8918194 | Current Opinion in Systems Biology | 2017 | 11 Pages |
Abstract
Over the past decade, a number of methods have emerged for inferring protein-level transcription factor activities in individual samples based on prior information about the structure of the gene regulatory network. We discuss how this has enabled new approaches for dissecting trans-acting mechanisms that underpin genetic variation in gene expression.
Related Topics
Physical Sciences and Engineering
Computer Science
Computer Science (General)
Authors
Harmen J. Bussemaker, Helen C. Causton, Mina Fazlollahi, Eunjee Lee, Ivor Muroff,