| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8920162 | Cell Regeneration | 2012 | 8 Pages |
Abstract
The results from intact and permeabilized MSCs indicate MRL-MSCs exhibit a greater reliance on and capacity for aerobic metabolism. The greater capacity for oxidative metabolism may provide a protective effect by increasing ATP synthesis per unit substrate and prevent glycolysis-mediated acidosis and subsequent cell death upon transplantation into the glucose-and oxygen-deprived environment of the infarcted heart.
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Authors
Curtis C Hughey, Maria P Alfaro, Darrell D Belke, Jeffery N Rottman, Pampee P Young, David H Wasserman, Jane Shearer,