| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8955942 | Biochemical and Biophysical Research Communications | 2018 | 7 Pages |
Abstract
Bcl-2 inhibition in NPC cells with ABT-199 triggers apoptosis through the Bcl-2/Noxa/Mcl-1 axis, and dual inhibition of the anti-apoptotic Bcl-2 family proteins Bcl-2 and Mcl-1 provided a strong synergistic effect without the need for adjunctive cytotoxic agent treatment with cisplatin.
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Authors
Yujie Wang, Yuyang Wang, Xiaoqin Fan, Jian Song, Hanwei Wu, Jinghong Han, Lu Lu, Xin Weng, Guohui Nie,