Attenuation of high glucose induced apoptotic and inflammatory signaling pathways in RIN-m5F pancreatic Î² cell lines by Hibiscus rosa sinensis L. petals and its phytoconstituents

Article ID	Journal	Published Year	Pages	File Type
8956555	Journal of Ethnopharmacology	2018	34 Pages	PDF

Keywords

NF-κB NK6 homeobox 1 Hibiscus rosa sinensis Urocortin-3 Nkx6.1 MafA Pdx1 EHRs IFN-γ IL-1β iNOS INS IL-6 FOXO1 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide AO/EB MTT NRU ROS Pancreatic β-cells acridine orange/ethidium bromide Ferulic acid (PubChem CID: 445858)interleukin 1-beta interleukin-6 Oxidative stress tumor necrosis factor alpha neutral red uptake TNF-α nuclear factor-κB Myricetin (PubChem CID: 5281672)Inflammatory markers nitric oxide synthase Insulin gene Interferon gamma Reactive oxygen species

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Attenuation of high glucose induced apoptotic and inflammatory signaling pathways in RIN-m5F pancreatic Î² cell lines by Hibiscus rosa sinensis L. petals and its phytoconstituents

Authors

Sneha S. Pillai, S. Mini,