Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8957014 | Diabetes & Metabolic Syndrome: Clinical Research & Reviews | 2018 | 20 Pages |
Abstract
Statistically significant increase in the levels of MMP-9, insulin, fasting blood glucose and lipid profile were observed in the serum of T2DM patients with retinopathy, as compared with those without retinopathy. These results help to conclude that rise in MMP-9, and associated serum markers promote disease progress in DR. These findings suggest that the elevations of our study markers in the serum of the type 2 diabetic patients with retinopathy, as compared to those without retinopathy, play important roles in aggravating tissue matrix degradation, supporting DR disease progression.
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Authors
Kuppuswami Jayashree, Md. Yasir, Gandhipuram Periyasamy Senthilkumar, K Ramesh Babu, Vadivelan Mehalingam, Palani Selvam Mohanraj,