| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8961967 | Peptides | 2018 | 33 Pages |
Abstract
In this paper we reviewed current knowledge about the relationship between chemerin and lower gastrointestinal (GI) diseases, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD) and colorectal cancer (CRC). A more detailed understanding of the role of the adipose tissue in the GI tract will not only unravel the pathophysiology of chronic intestinal diseases, but may also indicate a new therapeutic tool for their management.
Keywords
TLRIBDIBSIFN-γGPCRHDLDSSDCsIL-6mDCsCMKLR1chemokine-like receptor 1AMPKAdipokinesFACITPolyunsaturated fatty acidsPUFAinterferon γinterleukin 6White adipose tissueCrohn’s diseaseInflammatory bowel diseasetumor necrosis factor αGastrointestinalWaist circumferenceColorectal cancerT cellDendritic cellsirritable bowel syndromeDextran sulfate sodiumbody mass indexBMITNF-αT lymphocyteshigh density lipoproteinlow density lipoproteinLDLC-reactive proteinCRPChemerinWATCRChealthy controlToll-like receptorsG protein-coupled receptor
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Authors
Marcin Sochal, Paula MosiÅska, Jakub Fichna,