Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8963257 | Progress in Cardiovascular Diseases | 2018 | 46 Pages |
Abstract
The main purposes of this study were to elucidate the effects of supervised-exercise training (ET) interventions on hepatic fat content and on non-alcoholic fatty liver disease (NAFLD) prevalence in children and adolescents and to provide information about the optimal ET prescription (type, intensity, volume, and frequency) needed to reduce hepatic fat content in youths. Supervised-ET interventions performed in children and adolescents (6-19â¯years) that provided results of exercise effects on hepatic fat content or NAFLD prevalence were included. Supervised-exercise significantly reduced hepatic fat content compared to the control groups. Lifestyle interventions that included supervised-ET significantly reduced the prevalence of NAFLD. This systematic review and meta-analysis shows that supervised-ET could be an effective strategy in the management and prevention of NAFLD in children and adolescents. Both aerobic and resistance ET, at vigorous or moderate-to-vigorous intensities, with a volume â¥60â¯min/session and a frequency â¥3 sessions/week, aiming to improve cardiorespiratory fitness and muscular strength, had benefits on hepatic fat content reduction in youth. These data concur with the international recommendations of physical activity for health promotion in youth and may be useful when designing ET programs to improve and prevent hepatic steatosis in the pediatric population.
Keywords
RCTNAFLDone-repetition maximumProspero1RMModerate intensityEPHPPPICOSVO2maxT2DPRISMACRFAETRandomized controlled trialCardiorespiratory fitnessPreferred Reporting Items for Systematic reviews and Meta-analysisEffect sizeITTcardiovascular diseasenon-alcoholic fatty liver diseaseExercise trainingInternational Prospective Register of Systematic ReviewsType 2 diabetesCVDconfidence intervalsPhysical activityMuscular strengthintention-to-treatMaximum Oxygen Consumptionodd ratioAdolescentexerciseLiver fatChildrencontrol group
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Authors
MarÃa Medrano, Cristina Cadenas-Sanchez, Celia Álvarez-Bueno, Iván Cavero-Redondo, Jonatan R. Ruiz, Francisco B. Ortega, Idoia Labayen,