Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8993145 | Drug Metabolism and Pharmacokinetics | 2005 | 8 Pages |
Abstract
A theoretical approach using a simulation technique was also examined to evaluate the predictive performance. The results suggested that the predictability at the peak was not necessarily good at all sampling times and the predictability at the trough was better when a later time point was used. The optimal sampling time for prediction of VCM concentration in pediatric patients is discussed.
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Drug Discovery
Authors
Ayako Ohnishi, Yoshitaka Yano, Toru Ishibashi, Takayuki Katsube, Takayoshi Oguma,