Article ID Journal Published Year Pages File Type
8993357 Il Farmaco 2005 4 Pages PDF
Abstract
A Fourier transform infrared (FT-IR) spectrometric method was developed for the rapid, direct measurement of bucillamine. Conventional KBr-spectra and DRIFTS spectra were compared for best determination of active substance in its tablet formulation. Two chemometric approaches, partial least squares (PLS) and principal component regression (PCR+) methods were used in data processing. Similar results were obtained with both chemometric methods.
Keywords
Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Drug Discovery
Preview
Quantitative analysis of bucillamine and its pharmaceutical formulation using FT-IR spectroscopy
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