Ligand-dependent modulation of hOCT1 transport reveals discrete ligand binding sites within the substrate translocation channel

Article ID	Journal	Published Year	Pages	File Type
9004381	Biochemical Pharmacology	2018	49 Pages	PDF

Keywords

hOCT1 CHARMm CCF HEK OCT1 1-methyl-4-phenylpyridinium TMD MPP+PCA empty vector Tetraethylammonium Principal component analysis drug-drug interactions Anion transport organic cation transporter 1 Transmembrane domains Chemistry at HARvard Macromolecular Mechanics ligand-binding site TEA human embryonic kidney

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology

Ligand-dependent modulation of hOCT1 transport reveals discrete ligand binding sites within the substrate translocation channel

Authors

Kelli H. Boxberger, Bruno Hagenbuch, Jed N. Lampe,