| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9006907 | Fitoterapia | 2005 | 6 Pages |
Abstract
The cardioprotective effect of Prunella vulgaris ethylacetate fraction (PVEF) and its constituent rosmarinic acid (RA) was evaluated on isolated rat cardiomyocytes subjected to doxorubicin-induced oxidative stress. The cytoprotectivities of PVEF and RA were concentration-dependent in the range of 0.005 to 0.05 mg/ml and the effect of PVEF correlated with the RA content. Dexrazoxan (DE), used as positive control, was less effective than PVEF or RA.
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Authors
J. Psotová, S. ChlopÄÃková, P. Miketová, V. Å imánek,