| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9006997 | Fitoterapia | 2005 | 6 Pages |
Abstract
The estrogenic activity of a polyphenolic extract of the leaves of Epimedium brevicornum and five fractions obtained by solid-phase extraction were investigated using estrogen-responsive bioassays, a yeast cell assay and the Ishikawa Var-I assay. The extract was found to exhibit significant estrogenic activity in both assays. Furthermore, bioassay-guided fractionation led to localisation of the estrogenicity in the relatively non-polar fractions of the polyphenolic extract.
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Authors
An De Naeyer, Victoria Pocock, Stuart Milligan, Denis De Keukeleire,