Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9009680 | Journal of Ethnopharmacology | 2005 | 6 Pages |
Abstract
The anti-inflammatory activity of Lantana trifolia (Verbenaceae) was determined by carrageenan, serotonin and histamine-induced rat paw edema and the analgesic activity of this plant was studied by acetic acid-induced writhings and tail flick tests in mice. Lantana trifolia extracts (at 30Â mg/kg) inhibited carrageenan and histamine-induced rat paw edema. Although the extracts did not produce any effect on acetic acid-induced writhings, they all develop a significant increase on tail flick antinociceptive index (doses varying between 1 and 30Â mg/kg), indicating a spinal antinociceptive effect. These results provide support for the use of Lantana trifolia in relieving inflammatory pain.
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Authors
Glauce N. Silva, FabÃola R. Martins, Maria Eline Matheus, Suzana G. Leitão, Patricia D. Fernandes,