| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9009691 | Journal of Ethnopharmacology | 2005 | 4 Pages |
Abstract
The hypoglycemic effects of water, ethanolic and butanolic extracts prepared from the root of Malmea depressa (Baill) R.E. Fries. (Annonaceae) were studied in diabetic rats (streptozotocin induced). Oral application of water extracts at doses of 40 and 80Â mg/kg, ethanolic (112Â mg/kg) and butanolic (80Â mg/kg) extracts significantly lowered the plasma glucose levels in diabetic rats within three hours. Glibenclamide and metformin were used as references and showed similar hypoglycemic effects like the extracts. The three extracts have a similar chemical composition (HPLC analysis).
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Authors
Adolfo Andrade-Cetto, Eddy MartÃnez-Zurita, Helmut Wiedenfeld,