| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9009705 | Journal of Ethnopharmacology | 2005 | 8 Pages |
Abstract
The present study was undertaken to evaluate antimutagenic and cytotoxic effects of different extracts/fractions of Acacia nilotica prepared by maceration method. The potency order of different extracts was more or less similar in Ames assay as well as in cytotoxic assay. Considering the maximum potential of acetone extract in both the assays, the studies were initiated to fractionate this extract. Two pure fractions, namely AN-1 and AN-2, were obtained from acetone extract, of which AN-2 was found to be of gallic acid and AN-1 fraction is still to be identified. In conclusion, the antimutagenic and cytotoxic activities exhibited by acetone extract may partially be ascribed to the presence of gallic acid and other polyphenols.
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Authors
Kamaljit Kaur, Husheem Michael, Saroj Arora, Pirkko Härkönen, Subodh Kumar,