| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9009823 | Journal of Ethnopharmacology | 2005 | 5 Pages |
Abstract
Fruits of Heteropterys glabra (Malpighiaceae) are used in South-American folk medicine as a sedative and anxiolytic agent. In present research, we studied neurophysiological effects of the plant. Ethanolic extract was assayed in DBA/2J mice in order to evaluate the sleep wakefulness cycle, electroencephalogram (EEG) and visual evoked potentials (VEP). The results of our experiments indicated that the EtOH extract of the plant induced a reduction of motor activity and alterations of EEG and VEP parameters, supporting the possibility that the plant acts as an anxiolytic/sedative agent, thus, confirming its usual assumption and the traditional use.
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Authors
Gabriella Galietta, Giusi Giuliani, Alberto Loizzo, Anibal G. Amat, Emiliano Fumagalli, Vincenzo De Feo, Emilia Quaranta, Lidia Paladino, Anna Capasso,