| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9011197 | Journal of Ethnopharmacology | 2005 | 9 Pages |
Abstract
Our results have shown that LRT were demonstrated on the accumulation of eosinophills into airways, with reduction of eosinophil, total lung leukocytes numbers by reduction IL-5, IL-13, IL-4 and IgE levels in the BALF and serum. Moreover, LRT decreased eosinophil CCR3 expression and CD11b expression in lung cells. These results indicate that LRT has a deep inhibitory effects on airway inflammation and hyperresponsiveness in murine model of asthma and play an crucial role as a immunomodulator which possess anti-inflammatory and anti-asthmatic property by modulating the relationship between Th1/Th2 cytokine imbalance.
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Authors
Young-Cheol Lee, Jang-Cheon Lee, Young-Bae Seo, Yoon-Bum Kook,