Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9012241 | Journal of Pharmacological and Toxicological Methods | 2005 | 6 Pages |
Abstract
The value of doing the FOB as part of the safety pharmacology 'core battery' is emphasised by the fact that, even for non-CNS targeted compounds, the majority affected at least one of the parameters in the FOB. These data may also help to anticipate the most frequently required 'follow-up' studies.
Keywords
Related Topics
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Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
William S. Redfern, Isobel Strang, Sharon Storey, Clive Heys, Claire Barnard, Katherine Lawton, Tim G. Hammond, Jean-Pierre Valentin,