Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9012246 | Journal of Pharmacological and Toxicological Methods | 2005 | 13 Pages |
Abstract
Automation of electrophysiology technologies has greatly improved the throughput of assessing lead drug candidates for hERG liability. To maintain hERG data quality comparable to standard patch clamp techniques, the PatchXpress 7000A instrument limitations should be recognized and protocols optimized accordingly to ensure accuracy.
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Liang Guo, Heather Guthrie,