Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9014904 | Pharmacological Research | 2005 | 8 Pages |
Abstract
Based on the results obtained it is assumed that either the bioavailability of the betalains is low or that renal clearance is a minor route of systemic elimination for these compounds. The urinary excretion rates of unmetabolised betalains were fast and appeared to be monoexponential suggesting a one-compartment model. In order to get a more complete picture of the pharmacokinetics and health-promoting properties of red beet betalains, quantitative data on betalain bioavailability should include measurements of unchanged compounds and their corresponding metabolites in plasma, urine and bile.
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Authors
Thomas Frank, Florian Conrad Stintzing, Reinhold Carle, Irmgard Bitsch, Daniela Quaas, Gabriele StraÃ, Roland Bitsch, Michael Netzel,