Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9155487 | American Heart Journal | 2005 | 7 Pages |
Abstract
When adjusted for relevant covariates, compared with normal counterparts, overweight and obese patients with acute CHF have lower circulating NT-proBNP and BNP levels, suggesting a BMI-related defect in natriuretic peptide secretion. NT-proBNP fell below the diagnostic cutoff for CHF less often than BNP in overweight and obese individuals; however, when used as a diagnostic tool to identify CHF in such patients, both markers may have reduced sensitivity.
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Authors
Daniel G. MD, Donald M. MD, ScM, Claudia U. MD, MPH, Renee MS, Saif MD, Aaron L. MD, Annabel MD, Roderick MD, James L. MD,