Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9186317 | Trends in Cardiovascular Medicine | 2005 | 6 Pages |
Abstract
In this review, we focus on the role of conduction abnormalities in the genesis of arrhythmias in nonischemic dilated cardiomyopathy and discuss their underlying cellular and molecular mechanisms, including changes in myocyte excitability, the extracellular matrix, and cell-to-cell coupling. We compare the nature of conduction slowing in ischemic and nonischemic heart failure and highlight the mechanistic differences between the two disease etiologies.
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Authors
Fadi G. Akar, Gordon F. Tomaselli,