Article ID Journal Published Year Pages File Type
9194527 Journal of Neuroimmunology 2005 5 Pages PDF
Abstract
Lyme disease is a multi-systemic infection that causes diverse neurologic dysfunction collectively known as neuroborreliosis. In the murine model of Lyme disease, Borrelia burgdorferi are seldom found in the nervous system indicating that the spirochetes are rapidly cleared from the brain and peripheral nerves. In the present study, we examined the interaction between microglia and B. burgdorferi. Murine microglia are efficient phagocytes and are capable of ingesting and killing spirochetes with or without opsonization.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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