| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9268377 | Journal of Clinical Virology | 2005 | 5 Pages |
Abstract
In patients experienced with NRTIs, failure to PI-containing regimen may occur in spite of appropriate adherence to therapy and is associated with emergence of PI mutations in half of the cases. These results suggest that, although PIs have a high genetic barrier, sub-optimal activity of associated drugs may favor the selection of PI resistance mutations.
Keywords
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Authors
Diane Descamps, Véronique Joly, Philippe Flandre, Gilles Peytavin, Vincent Meiffrédy, Séverine Delarue, Stéphane Lastère, Jean-Pierre Aboulker, Patrick Yeni, Françoise Brun-Vézinet,