| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9268420 | Journal of Clinical Virology | 2005 | 5 Pages |
Abstract
This study supports that current treatment by NRTI is a main determinant of mtDNA depletion in adipose tissue of HIV-seropositive patients with peripheral fat wasting. Stavudine or didanosine current intake is significantly associated with mtDNA depletion in vivo, that could be reversible after the discontinuation of these molecules, when considering mtDNA level according to current use versus past use of these molecules.
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Authors
Marc Buffet, Michaël Schwarzinger, Bahia Amellal, Karine Gourlain, Patrick Bui, Marianne Prévot, Jean Deleuze, Jean-Pierre Morini, Isabelle Gorin, Vincent Calvez, Nicolas Dupin,